{"id":1403,"date":"2020-08-24T15:46:00","date_gmt":"2020-08-24T18:46:00","guid":{"rendered":"https:\/\/revista.suryamkt.com.br\/?p=1403"},"modified":"2022-02-09T15:51:43","modified_gmt":"2022-02-09T18:51:43","slug":"successful-treatment-of-severely-cholestatic-acute-hepatitis-b-with-oral-corticosteroid","status":"publish","type":"post","link":"https:\/\/revistaabcd.org.br\/pt-br\/successful-treatment-of-severely-cholestatic-acute-hepatitis-b-with-oral-corticosteroid\/","title":{"rendered":"SUCCESSFUL TREATMENT OF SEVERELY CHOLESTATIC ACUTE HEPATITIS B WITH ORAL CORTICOSTEROID"},"content":{"rendered":"<h2 class=\"wp-block-heading\">INTRODUCTION<\/h2>\n\n\n\n<p>Acute hepatitis B (HBV) infection is asymptomatic, subclinical illness in approximately two thirds of cases and diagnosis is made only through serologic testing<sup>7<\/sup>. Clinical evidence of hepatitis; jaundice and occasionally acute liver failure develops in rest one third of patients with acute HBV infection<sup>7<\/sup>. Cholestatic hepatitis is one of very rare manifestations of acute HBV infection, but when develop it leads to prolonged hospital stay and increased medical expenses<sup>5<\/sup>. Rapid improvement of the clinical symptoms and signs have been reported in patients with cholestatic hepatitis A (HAV) after use of corticosteroid<sup>6<\/sup>. We here report a case of cholestatic hepatitis due to acute HBV infection and rapid improvement of symptoms with oral prednisolone. <a><\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">CASE REPORT<\/h2>\n\n\n\n<p>A 56-year old female patient presented with complaints of progressively increasing jaundice and intense pruritus that disturbed sleep for 12 weeks duration. She had been evaluated at a local hospital and diagnosed to have acute viral hepatitis due to hepatitis B virus infection (HBV) on the basis of raised liver enzymes and serological markers (<a href=\"https:\/\/www.scielo.br\/j\/abcd\/a\/7mcjc97w6QS3tLjGDzs7Fyn\/?lang=en\" rel=\"nofollow noopener\" target=\"_blank\">Table 1<\/a>).<\/p>","protected":false},"excerpt":{"rendered":"<p>INTRODUCTION Acute hepatitis B (HBV) infection is asymptomatic, subclinical illness in approximately two thirds of cases and diagnosis is made only through serologic testing7. Clinical evidence of hepatitis; jaundice and occasionally acute liver failure develops in rest one third of patients with acute HBV infection7. Cholestatic hepatitis is one of very rare manifestations of acute [&hellip;]<\/p>","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[10],"tags":[360,362,361],"class_list":["post-1403","post","type-post","status-publish","format-standard","hentry","category-letter-to-the-editor","tag-cholestasis","tag-corticosteroid","tag-hepatitis-b"],"acf":[],"modified_by":null,"_links":{"self":[{"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/posts\/1403"}],"collection":[{"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/comments?post=1403"}],"version-history":[{"count":0,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/posts\/1403\/revisions"}],"wp:attachment":[{"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/media?parent=1403"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/categories?post=1403"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/tags?post=1403"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}