The identification of prognostic factors of esophageal cancer has allowed to predict the evolution of patients.<\/p>\n\n\n\n
Assess different prognostic factors of long-term survival of esophageal cancer and evaluate a new prognostic factor of long-term survival called lymphoparietal index (N+\/T).<\/p>\n\n\n\n
Prospective study of the Universidad de Chile Clinical Hospital, between January 2004 and December 2013. Included all esophageal cancer surgeries with curative intent and cervical anastomosis. Exclusion criteria included: stage 4 cancers, R1 resections, palliative procedures and emergency surgeries.<\/p>\n\n\n\n
Fifty-eight patients were included, 62.1% were men, the average age was 63.3 years. A total of 48.3% were squamous, 88% were advanced cancers, the average lymph node harvest was 17.1. Post-operative surgical morbidity was 75%, with a 17.2% of reoperations and 3.4% of mortality. The average overall survival was 41.3 months, the 3-year survival was 31%. Multivariate analysis of the prognostic factors showed that significant variables were anterior mediastinal ascent (p=0.01, OR: 6.7 [1.43-31.6]), anastomotic fistula (p=0.03, OR: 0.21 [0.05-0.87]), N classification (p=0.02, OR: 3.8 [1.16-12.73]), TNM stage (p=0.04, OR: 2.8 [1.01-9.26]), and lymphoparietal index (p=0.04, RR: 3.9 [1.01-15.17]. The ROC curves of lymphoparietal index, N classification and TNM stage have areas under the curve of 0.71, 0.63 and 0.64 respectively, with significant statistical difference (p=0.01).<\/p>\n\n\n\n
The independent prognostic factors of long-term survival in esophageal cancer are anterior mediastinal ascent, anastomotic fistula, N classification, TNM stage and lymphoparietal index. In esophageal cancer the new lymphoparietal index is stronger than TNM stage in long-term survival prognosis.<\/p>","protected":false},"excerpt":{"rendered":"
Background: The identification of prognostic factors of esophageal cancer has allowed to predict the evolution of patients. Aim: Assess different prognostic factors of long-term survival of esophageal cancer and evaluate a new prognostic factor of long-term survival called lymphoparietal index (N+\/T). Method: Prospective study of the Universidad de Chile Clinical Hospital, between January 2004 and […]<\/p>","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[9],"tags":[187,127,381],"class_list":["post-1534","post","type-post","status-publish","format-standard","hentry","category-original-article","tag-esophageal-neoplasms","tag-prognosis","tag-survival"],"acf":{"authors":[{"author_name":"Manuel FIGUEROA-GIRALT","orcid_id":"http:\/\/orcid.org\/0000-0003-4907-5727"},{"author_name":"Catalina VALENZUELA","orcid_id":"http:\/\/orcid.org\/0000-0002-7283-4835"},{"author_name":"Andr\u00e9s TORREALBA","orcid_id":"http:\/\/orcid.org\/0000-0003-3084-1858"},{"author_name":"Attila CSENDES","orcid_id":"http:\/\/orcid.org\/0000-0002-7524-8057"},{"author_name":"Italo BRAGHETTO","orcid_id":"http:\/\/orcid.org\/0000-0003-2024-3029"},{"author_name":"Enrique LANZARINI","orcid_id":"http:\/\/orcid.org\/0000-0003-2817-3889"},{"author_name":"Maher MUSLEH","orcid_id":"http:\/\/orcid.org\/0000-0002-4717-0336"},{"author_name":"Owen KORN","orcid_id":"http:\/\/orcid.org\/0000-0001-7840-2534"},{"author_name":"Hector VALLADARES","orcid_id":"http:\/\/orcid.org\/0000-0001-9477-176X"},{"author_name":"Solange CORT\u00c9S","orcid_id":"http:\/\/orcid.org\/0000-0002-6740-104X"}],"doi":"10.1590\/0102-672020200003e1547","buttons":{"pdf_-_en":1536,"pdf_-_pt":1535,"external_link":"https:\/\/www.scielo.br\/j\/abcd\/a\/ZpwZMRVmhDzT49zYH3TXJvF\/?lang=en","external_link_pt":"https:\/\/www.scielo.br\/j\/abcd\/a\/ZpwZMRVmhDzT49zYH3TXJvF\/?lang=pt","full_text":"","jats_xml":""},"volume_and_issue":{"article-volume":"2020 - vol. 33","article-issue":"Issue 3"}},"modified_by":null,"_links":{"self":[{"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/posts\/1534","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/comments?post=1534"}],"version-history":[{"count":0,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/posts\/1534\/revisions"}],"wp:attachment":[{"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/media?parent=1534"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/categories?post=1534"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/tags?post=1534"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}