{"id":6124,"date":"2025-05-30T17:37:59","date_gmt":"2025-05-30T20:37:59","guid":{"rendered":"https:\/\/revistaabcd.org.br\/?p=6124"},"modified":"2025-05-30T17:37:59","modified_gmt":"2025-05-30T20:37:59","slug":"impact-of-sleeve-gastrectomy-on-the-neutrophil-to-lymphocyte-ratio-and-the-platelet-to-lymphocyte-ratio-and-its-relationship-with-postoperative-weight-loss","status":"publish","type":"post","link":"https:\/\/revistaabcd.org.br\/pt-br\/impact-of-sleeve-gastrectomy-on-the-neutrophil-to-lymphocyte-ratio-and-the-platelet-to-lymphocyte-ratio-and-its-relationship-with-postoperative-weight-loss\/","title":{"rendered":"IMPACT OF SLEEVE GASTRECTOMY ON THE NEUTROPHIL-TO-LYMPHOCYTE RATIO AND THE PLATELET-TO-LYMPHOCYTE RATIO AND ITS RELATIONSHIP WITH POSTOPERATIVE WEIGHT LOSS"},"content":{"rendered":"<h2>BACKGROUND<strong>:\u00a0<\/strong><\/h2>\n<p>Obesity represents a chronic pro-inflammatory status that contributes to accelerated atherosclerosis and cell aging. Besides the widely used C-reactive protein and ferritin, other inflammatory markers have gained attention, such as neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR), which are related with the degree of inflammation in various pathological conditions, including obesity and its comorbidities.<\/p>\n<h2>AIMS<strong>:\u00a0<\/strong><\/h2>\n<p>To compare and monitor the levels of NLR and PLR before and after sleeve gastrectomy (SG).<\/p>\n<h2>METHODS:<\/h2>\n<p>Retrospective study that included a total of 622 patients with obesity who underwent SG as primer bariatric surgery in our center. Data regarding the presence of comorbidities, including type 2 diabetes (T2D), high blood pressure (HBP) and non-alcoholic fatty liver disease (NAFLD), variations in body weight and body mass index (BMI), and biochemical markers of inflammation, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and C-reactive protein (CRP) were gathered. Values of NLR and PLR were correlated with weight loss and prognosis of comorbidities within the postoperative period.<\/p>\n<h2>RESULTS:<\/h2>\n<p>The sample was predominantly female (79.3%) with average age 36.91\u00b110.04 years, with comorbidities including HBP (25.1%), T2D (8.0%), and NAFLD (80.1%). Patients with HBP showed reduced NLR and CRP post-intervention, while those with T2D experienced decreased CRP but increased PLR. Correlation analysis found no significant correlation between BMI\/weight changes and NLR but significant correlation with PLR. Post-surgery, NLR decreased for previously NAFLD patients, and PLR increased.<\/p>\n<h2>CONCLUSIONS:<\/h2>\n<p>According to the results, patients with obesity present a significant decrease in NLR and an increase in PLR after SG.<\/p>","protected":false},"excerpt":{"rendered":"<p>BACKGROUND:\u00a0 Obesity represents a chronic pro-inflammatory status that contributes to accelerated atherosclerosis and cell aging. Besides the widely used C-reactive protein and ferritin, other inflammatory markers have gained attention, such as neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR), which are related with the degree of inflammation in various pathological conditions, including obesity and its comorbidities. [&hellip;]<\/p>","protected":false},"author":14,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[9],"tags":[122,143,637,43],"class_list":["post-6124","post","type-post","status-publish","format-standard","hentry","category-original-article","tag-bariatric-surgery","tag-inflammation","tag-inflammation-mediators","tag-obesity"],"acf":[],"modified_by":"Rodrigo","_links":{"self":[{"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/posts\/6124"}],"collection":[{"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/users\/14"}],"replies":[{"embeddable":true,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/comments?post=6124"}],"version-history":[{"count":2,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/posts\/6124\/revisions"}],"predecessor-version":[{"id":6127,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/posts\/6124\/revisions\/6127"}],"wp:attachment":[{"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/media?parent=6124"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/categories?post=6124"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/tags?post=6124"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}