{"id":6170,"date":"2025-07-08T16:05:37","date_gmt":"2025-07-08T19:05:37","guid":{"rendered":"https:\/\/revistaabcd.org.br\/?p=6170"},"modified":"2025-07-08T16:05:37","modified_gmt":"2025-07-08T19:05:37","slug":"which-lesions-are-at-higher-risk-of-developing-colorectal-carcinomas-superficially-elevated-serrated-lesions-or-depressed-lesions","status":"publish","type":"post","link":"https:\/\/revistaabcd.org.br\/pt-br\/which-lesions-are-at-higher-risk-of-developing-colorectal-carcinomas-superficially-elevated-serrated-lesions-or-depressed-lesions\/","title":{"rendered":"WHICH LESIONS ARE AT HIGHER RISK OF DEVELOPING COLORECTAL CARCINOMAS: SUPERFICIALLY ELEVATED SERRATED LESIONS OR DEPRESSED LESIONS?"},"content":{"rendered":"<h2><strong>BACKGROUND:<\/strong><\/h2>\n<p>There are lesions that are still being missed in colonoscopy. Many of those could be superficially elevated serrated lesions or depressed ones.<\/p>\n<h2><strong>AIMS:<\/strong><\/h2>\n<p>The aim of this study was to compare the histopathological characteristics of these lesions and their risks for submucosal carcinoma.<\/p>\n<h2><strong>METHODS:<\/strong><\/h2>\n<p>This is a retrospective, cross-sectional, and observational study comparing 217 superficially elevated serrated lesions larger than 5\u00a0mm resected by colonoscopies (G1) with 558 depressed lesions (G2).<\/p>\n<h2><strong>RESULTS:<\/strong><\/h2>\n<p>In G1, 217 lesions were found in 12,653 (1.7%) colonoscopies; in G2, 558 lesions were found in 36,174 (1.5%) colonoscopies. In G1, 63.4% were women and in G2, there was no gender predominance. The average size of G1 was 16.2\u00a0mm and G2 was 9.2\u00a0mm (p&lt;0.001). G1 predominated on the proximal colon and G2 on the distal and rectum (p&lt;0.001). In G1, there were 214 (98.6%) low-grade intramucosal neoplasia and 3 (1.4%) high-grade intramucosal neoplasia. Excluding 126 hyperplastic polyps and considering 91 sessile serrated adenomas in G1, we observed 88 (96.7%) low-grade intramucosal neoplasia and 3 (3.3%) high-grade intramucosal neoplasia; in G2, we observed 417 (74.7%) low-grade intramucosal neoplasia, 113 (20.3%) high-grade intramucosal neoplasia, and 28 (5.0%) submucosal adenocarcinomas (p&lt;0.001).<\/p>\n<h2><strong>CONCLUSION:<\/strong><\/h2>\n<p>Depressed lesions significantly had more high-grade intramucosal neoplasia and more invasive carcinomas in the submucosal layer than superficially elevated serrated lesions and more than superficially elevated sessile serrated adenomas.<\/p>","protected":false},"excerpt":{"rendered":"<p>BACKGROUND: There are lesions that are still being missed in colonoscopy. Many of those could be superficially elevated serrated lesions or depressed ones. AIMS: The aim of this study was to compare the histopathological characteristics of these lesions and their risks for submucosal carcinoma. METHODS: This is a retrospective, cross-sectional, and observational study comparing 217 [&hellip;]<\/p>","protected":false},"author":14,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[9],"tags":[616,294,94,1272,1246],"class_list":["post-6170","post","type-post","status-publish","format-standard","hentry","category-original-article","tag-colon","tag-colonoscopy","tag-colorectal-neoplasms","tag-mass-screening","tag-polyps"],"acf":[],"modified_by":"Rodrigo","_links":{"self":[{"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/posts\/6170"}],"collection":[{"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/users\/14"}],"replies":[{"embeddable":true,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/comments?post=6170"}],"version-history":[{"count":2,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/posts\/6170\/revisions"}],"predecessor-version":[{"id":6173,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/posts\/6170\/revisions\/6173"}],"wp:attachment":[{"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/media?parent=6170"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/categories?post=6170"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/revistaabcd.org.br\/pt-br\/wp-json\/wp\/v2\/tags?post=6170"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}