{"id":6636,"date":"2026-08-19T17:38:39","date_gmt":"2026-08-19T20:38:39","guid":{"rendered":"https:\/\/revistaabcd.org.br\/prevention-surveillance-and-early-detection-of-hepatocellular-carcinoma-a-brazilian-multidisciplinary-consensus\/"},"modified":"2026-08-19T19:04:23","modified_gmt":"2026-08-19T22:04:23","slug":"prevention-surveillance-and-early-detection-of-hepatocellular-carcinoma-a-brazilian-multidisciplinary-consensus","status":"publish","type":"post","link":"https:\/\/revistaabcd.org.br\/pt-br\/prevention-surveillance-and-early-detection-of-hepatocellular-carcinoma-a-brazilian-multidisciplinary-consensus\/","title":{"rendered":"Prevention, surveillance, and early detection of hepatocellular carcinoma - a Brazilian multidisciplinary consensus"},"content":{"rendered":"
\"Visual<\/figure>\n

Background<\/strong><\/h2>\n

Hepatocellular carcinoma is a major cause of cancer-related mortality and represents a growing public health challenge.<\/p>\n

Aims<\/strong><\/h2>\n

To develop multidisciplinary evidence-based recommendations for the prevention and early detection of hepatocellular carcinoma.<\/p>\n

Methods<\/strong><\/h2>\n

This consensus was coordinated by the Brazilian Society of Surgical Oncology, with the participation of 13 additional national societies. A steering committee defined the key clinical questions addressing prevention, surveillance, and early detection strategies. Recommendation statements were informed by a comprehensive, non-systematic review of the literature conducted using PubMed, Scopus, and the Cochrane Library.<\/p>\n

Results<\/strong><\/h2>\n

Eighteen recommendations reached consensus, covering three main domains: 1. Primary prevention, including HBV vaccination, timely antiviral therapy for viral hepatitis, and lifestyle interventions for metabolic dysfunction. 2. Secondary prevention, outlining risk-based surveillance strategies for patients with advanced fibrosis or cirrhosis due to hepatitis B virus, hepatitis C virus, or metabolic dysfunction-associated steatotic liver disease. 3. Operational standards for surveillance, emphasizing ultrasound as the cornerstone of monitoring, the importance of structured reporting, management of small nodules, and the selective use of cross-sectional imaging.<\/p>\n

Conclusions<\/strong><\/h2>\n

These multidisciplinary recommendations provide practical, adaptable guidance for the prevention, surveillance, and early detection of hepatocellular carcinoma. This guidance document aims to reduce the burden of hepatocellular carcinoma and support better clinical outcomes across diverse healthcare settings.<\/p>","protected":false},"excerpt":{"rendered":"

Background Hepatocellular carcinoma is a major cause of cancer-related mortality and represents a growing public health challenge. Aims To develop multidisciplinary evidence-based recommendations for the prevention and early detection of hepatocellular carcinoma. Methods This consensus was coordinated by the Brazilian Society of Surgical Oncology, with the participation of 13 additional national societies. A steering committee […]<\/p>","protected":false},"author":4,"featured_media":6643,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[11],"tags":[],"class_list":["post-6636","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-review-article"],"acf":{"authors":[{"author_name":"Felipe Jos\u00e9 Fern\u00e1ndez COIMBRA","orcid_id":"https:\/\/orcid.org\/0000-0001-5068-0639"},{"author_name":"Andr\u00e9 Lu\u00eds de GODOY","orcid_id":"https:\/\/orcid.org\/0000-0002-7154-1184"},{"author_name":"Paulo Henrique de Sousa FERNANDES","orcid_id":"https:\/\/orcid.org\/0000-0001-5476-2017"},{"author_name":"Hel\u00e1dio Feitosa E CASTRO NETO","orcid_id":"https:\/\/orcid.org\/0000-0001-6455-916X"},{"author_name":"Rodrigo Nascimento PINHEIRO","orcid_id":"https:\/\/orcid.org\/0000-0002-2715-7628"},{"author_name":"Ilka de F\u00e1tima Santana Ferreira BOIN","orcid_id":"https:\/\/orcid.org\/0000-0002-1165-2149"},{"author_name":"Wellington ANDRAUS","orcid_id":"https:\/\/orcid.org\/0000-0002-5162-138X"},{"author_name":"Francisco TUSTUMI","orcid_id":"https:\/\/orcid.org\/0000-0001-6695-0496"},{"author_name":"Paulo Cezar Galv\u00e3o do AMARAL","orcid_id":"https:\/\/orcid.org\/0000-0002-2510-0193"},{"author_name":"Carlos Eduardo BRAND\u00c3O-MELLO","orcid_id":"https:\/\/orcid.org\/0000-0001-8965-6556"},{"author_name":"Alexcia Camila BRAUN","orcid_id":"https:\/\/orcid.org\/0000-0002-9028-2026"},{"author_name":"Maria Ignez BRAGHIROLI","orcid_id":"https:\/\/orcid.org\/0000-0001-6366-8786"},{"author_name":"Luis C\u00e9sar BREDT","orcid_id":"https:\/\/orcid.org\/0000-0002-8587-1790"},{"author_name":"Carla CAPARROZ","orcid_id":"https:\/\/orcid.org\/0000-0002-0628-2016"},{"author_name":"Flair Jos\u00e9 CARRILHO","orcid_id":"https:\/\/orcid.org\/0000-0002-7682-3105"},{"author_name":"Guilherme Moura CUNHA","orcid_id":"https:\/\/orcid.org\/0000-0001-6403-5155"},{"author_name":"Alessandro Landskron DINIZ","orcid_id":"https:\/\/orcid.org\/0000-0001-9671-2026"},{"author_name":"Daniel Neves FORTE","orcid_id":"https:\/\/orcid.org\/0000-0003-1996-7193"},{"author_name":"Jos\u00e9 Huygens Parente GARCIA","orcid_id":"https:\/\/orcid.org\/0000-0002-5057-7903"},{"author_name":"T\u00e9rcio GENZINI","orcid_id":"https:\/\/orcid.org\/0000-0002-3589-3983"},{"author_name":"Mauro Monteiro CORREIA","orcid_id":"https:\/\/orcid.org\/0009-0005-4365-6899"},{"author_name":"C\u00e1ssio Virg\u00edlio Cavalcante de OLIVEIRA","orcid_id":"https:\/\/orcid.org\/0000-0001-8385-7656"},{"author_name":"Antonio Nocchi KALIL","orcid_id":"https:\/\/orcid.org\/0000-0002-2658-0731"},{"author_name":"Agnaldo Soares LIMA","orcid_id":"https:\/\/orcid.org\/0000-0001-6421-3062"},{"author_name":"Guilherme Lopes Pinheiro MARTINS","orcid_id":"https:\/\/orcid.org\/0000-0002-2617-2316"},{"author_name":"Cristina Melo ROCHA","orcid_id":"https:\/\/orcid.org\/0000-0002-3772-362X"},{"author_name":"Marcos Roberto de MENEZES","orcid_id":"https:\/\/orcid.org\/0000-0001-7548-8774"},{"author_name":"Joaquim Maur\u00edcio da MOTTA-LEAL-FILHO","orcid_id":"https:\/\/orcid.org\/0000-0001-9844-6833"},{"author_name":"Munir MURAD J\u00daNIOR","orcid_id":"https:\/\/orcid.org\/0009-0002-1791-8814"},{"author_name":"Renata D'Alpino PEIXOTO","orcid_id":"https:\/\/orcid.org\/0000-0003-0053-7951"},{"author_name":"Rafael Soares Nunes PINHEIRO","orcid_id":"https:\/\/orcid.org\/0000-0001-8632-3529"},{"author_name":"Marcelo Bruno de REZENDE","orcid_id":"https:\/\/orcid.org\/0000-0001-5594-033X"},{"author_name":"H\u00e9ber Salvador de Castro RIBEIRO","orcid_id":"https:\/\/orcid.org\/0000-0002-3412-7451"},{"author_name":"Mario Rino MARTINS","orcid_id":"https:\/\/orcid.org\/0000-0001-8705-8210"},{"author_name":"Duilio Reis da ROCHA FILHO","orcid_id":"https:\/\/orcid.org\/0000-0001-7756-1891"},{"author_name":"Arthur Accioly 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