Gastric stump cancer was first reported as a disease entity by Balfour in 19221,6. It was defined initially as cancer that arises in the remnant stomach after five years of gastrectomy for benign disease such as peptic ulcer1,6,8. Another opinion includes ten-year latency period after primary operation for benign or malignant disease. Cancer recurrence in the stump after ten years of gastrectomy is rare9.
The anatomical region most commonly affected is next to the anastomosis, gastric side. With a prevalence of 1-9% among cases of stomach cancer, it affects between 0.8-8.9% of patients who underwent partial gastric resection for peptic ulcer1.
Reduction in the prevalence of peptic ulcer gastrectomy is reported4,8,10 due to therapeutic advances, among them drug treatment by Helicobacter pylori infection8,10. However, surgery continues to be performed for the complications of peptic ulcer disease, such as perforation, bleeding or stenosis8.
In this article, the authors report two cases of gastric stump cancer after Billroth II gastrectomy for peptic ulcer disease.
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