Revista ABCd (São Paulo). 01 jan, 2016

ON VASCULAR STENOSIS, RESTENOSIS AND MANNOSE BINDING LECTIN

Barbara Stadler KAHLOW
Rodrigo Araldi NERY
Thelma L SKARE
Carmen Australia Paredes Marcondes RIBAS
Gabriela Piovezani Ramos
Roberta Dombroski Petisco
DOI: 10.1590/0102-6720201600010015

Mannose binding lectin is a lectin instrumental in the innate immunity. It recognizes carbohydrate patterns found on the surface of a large number of pathogenic micro-organisms, activating the complement system. However, this protein seems to increase the tissue damage after ischemia. In this paper is reviewed some aspects of harmful role of the mannose binding lectin in ischemia/reperfusion injury.


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