Revista ABCd (São Paulo). 05 Dec, 2024

THE GROWING EVIDENCE OF THE RELATIONSHIP BETWEEN OBESITY AND CANCER AND THE ROLE OF BARIATRIC SURGERY

Paulo KASSAB
Álvaro Antônio Bandeira FERRAZ
Anna Clara Hebling MITIDIERI
Luiz Vicente BERTI
Marco Aurélio SANTO
Tiago SZEGO
Caio de Carvalho ZANON
Osvaldo Antônio Prado CASTRO
Wilson Rodrigues de FREITAS JUNIOR
Elias Jirjoss ILIAS
Carlos Alberto MALHEIROS
Antônio Carlos VALEZ
Antônio Carlos Ligocki CAMPOS
DOI: https://doi.org/10.1590/0102-6720202400044e1838

Obesity is recognized as a significant risk factor for various types of cancer. Although the incidence of some types of cancer across various primary sites is decreasing due to specific prevention measures (screening programs, smoking cessation), the incidence of neoplasms in the young population shows a significant increase associated with obesity. There is sufficient evidence to say that bariatric surgery has been shown to significantly lower the risk of developing obesity-associated cancers, which are linked to metabolic dysregulation, chronic low-grade systemic inflammation, and hormonal alterations such as elevated levels of insulin and sex hormones.


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ABCD – BRAZILIAN ARCHIVES OF DIGESTIVE SURGERY is a periodic with a single annual volume in continuous publication, official organ of the Brazilian College of Digestive Surgery - CBCD. Technical manager: Dr. Francisco Tustumi | CRM: 157311 | RQE: 77151 - Cirurgia do Aparelho Digestivo

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