05 Jan, 2014

Use of alloplastic meshes in abdominal wounds of rats with induced peritonitis

Rafael Calvão BARBUTO
Ivana DUVAL-ARAUJO
Sumara Marques BARRAL
Raphael Grossi ROCHA
Cristiane de Souza BECHARA
Alfredo José Afonso BARBOSA
DOI: 10.1590/S0102-67202014000100007
Share this article

Background

: The use of alloplastic meshes has been historically contra-indicated in patients with infection.

Aim

: To evaluate the use of polypropylene meshes in the treatment of abdominal wall defects in rats with peritonitis.

Methods

: Twenty Wistar female rats were divided into two groups: induction of peritonitis (test group) and without peritonitis (control group). An abdominal wall defect was created in all animals, and polypropylene mesh was applied. The evaluation of the tensile strength of the mesh was carried out using tensiometer and microscopic analysis of the healing area was done.

Results

: More adhesion of the mesh to the rat abdominal wall was observed in test group. The histopathological analyses showed prevalence of moderate to accentuated granulation tissue in both groups, without significant differences.

Conclusion

: The use of the mesh coverage on abdominal wall defects of rats with induced peritonitis did not show worse results than its use in healthy animals, nor was its integration to the resident tissue any worse.


. . .
Indexed in:
Follow us!
ABCD – BRAZILIAN ARCHIVES OF DIGESTIVE SURGERY is a periodic with a single annual volume in continuous publication, official organ of the Brazilian College of Digestive Surgery - CBCD.

Developed by Surya MKT